H3F3A Antibody
Product Sizes
100 ug
£496.00
OAAF00945-100UG
About this Product
- SKU:
- OAAF00945
- Additional Names:
- H3 histone family member 3A;H3 histone family member 3B;H3 histone; family 3A;H3 histone; family 3B (H3.3B);H3.3A;H3.3B;H3-3A;H3-3B;H3F3;H3F3A;H3F3B;histone H3.3.
- Clonality:
- Polyclonal
- Extra Details:
- Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes; suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin; limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation; DNA repair; DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones; also called histone code; and nucleosome remodeling.
- Gene Details:
- H3.3 histone A|H3.3 histone B
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Histone H3.3.
- Molecular Weight:
- 15 kDa
- Protein Details:
- Histone H3.3
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
