BCL2 Antibody
Product Sizes
100 ug
£496.00
OAAF00934-100UG
About this Product
- SKU:
- OAAF00934
- Additional Names:
- apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1; regulatory subunit 50.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation; hence CASP1 activation and IL1B release (PubMed:17418785).
- Gene Details:
- BCL2 apoptosis regulator
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human BCL-2.
- Isotype:
- IgG
- Molecular Weight:
- 26 kDa
- Protein Details:
- Apoptosis regulator Bcl-2
- Purification:
- The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
