ADAM17 Antibody
Product Sizes
100 ug
£496.00
OAAF00924-100UG
About this Product
- SKU:
- OAAF00924
- Additional Names:
- a disintegrin and metalloproteinase 17;ADAM metallopeptidase domain 18;ADAM18;cartilage snake venom-like protease;CD156B;CSVP;disintegrin and metalloproteinase domain-containing protein 17;NISBD;NISBD1;snake venom-like protease;TACE;TNF-alpha convertase;TNF-alpha convertase enzyme;TNF-alpha converting enzyme;TNF-alpha-converting enzyme;tumor necrosis factor; alpha; converting enzyme.
- Clonality:
- Polyclonal
- Extra Details:
- Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins; including p75 TNF-receptor; interleukin 1 receptor type II; p55 TNF-receptor; transforming growth factor-alpha; L-selectin; growth hormone receptor; MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch; generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.
- Gene Details:
- ADAM metallopeptidase domain 17
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ADAM 17.
- Molecular Weight:
- 93 kDa
- Protein Details:
- Disintegrin and metalloproteinase domain-containing protein 17
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
