ITPR1 Antibody
Product Sizes
100 ug
£496.00
OAAF00552-100UG
About this Product
- SKU:
- OAAF00552
- Additional Names:
- ACV;CLA4;inositol 1;4;5-triphosphate receptor; type 1;inositol 1;4;5-trisphosphate receptor type 1;INSP3R1;IP3 receptor;IP3 receptor isoform 1;IP3R;IP3R 1;IP3R1;PPP1R94;protein phosphatase 1; regulatory subunit 94;SCA15;SCA16;SCA29;type 1 inositol 1;4;5-trisphosphate receptor;type 1 InsP3 receptor.
- Clonality:
- Polyclonal
- Extra Details:
- Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1;4;5-trisphosphate (PubMed:27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II; eventually leading to the activation of downstream apoptosis pathways (By similarity).
- Gene Details:
- inositol 1;4;5-trisphosphate receptor type 1
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human IP3R1 around the phosphorylation site of Ser1764.
- Molecular Weight:
- 313 kDa
- Protein Details:
- Inositol 1;4;5-trisphosphate receptor type 1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using n
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
