MAP3K9/MAP3K10 Antibody
Product Sizes
100 ug
£496.00
OAAF00460-100UG
About this Product
- SKU:
- OAAF00460
- Additional Names:
- MEKK10;MEKK9;mitogen-activated protein kinase kinase kinase 10;mitogen-activated protein kinase kinase kinase 9;Mixed lineage kinase 1;mixed lineage kinase 1 (tyr and ser/thr specificity);mixed lineage kinase 2;MKN28 derived nonreceptor_type serine/threonine kinase;MKN28 kinase;MLK1;MLK2;MST;PRKE1;protein kinase MST.
- Clonality:
- Polyclonal
- Extra Details:
- Activates the JUN N-terminal pathway.|Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated; acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway; including the release cytochrome c; leading to apoptosis.
- Gene Details:
- mitogen-activated protein kinase kinase kinase 10|mitogen-activated protein kinase kinase kinase 9
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MLK1/2 around the phosphorylation site of Thr312/266.
- Molecular Weight:
- 121 kDa
- Protein Details:
- Mitogen-activated protein kinase kinase kinase 10|Mitogen-activated protein kinase kinase kinase 9
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
