IKBKG Antibody
Product Sizes
100 ug
£496.00
OAAF00444-100UG
About this Product
- SKU:
- OAAF00444
- Additional Names:
- 14.7K (adenovirus E3 protein) interacting protein 3;AMCBX1;EDAID1;FIP3;FIP-3;Fip3p;I-kappa-B kinase subunit gamma;ikB kinase subunit gamma;ikB kinase-associated protein 1;IKKAP1;IKKG;IKK-gamma;IMD33;incontinentia pigmenti;inhibitor of kappa light polypeptide gene enhancer in B-cells; kinase gamma;inhibitor of nuclear factor kappa B kinase subunit gamma;Inhibitor of nuclear factor kappa-B kinase subunit gamma;IP;IP1;IP2;IPD2;NEMO;NF-kappa-B essential modifier;NF-kappa-B essential modulator;ZC2HC9.
- Clonality:
- Polyclonal
- Extra Details:
- Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However; the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.
- Gene Details:
- inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human IKK-gamma around the phosphorylation site of Ser376.
- Molecular Weight:
- 48 kDa
- Protein Details:
- NF-kappa-B essential modulator
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
