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Antibodies

ACO1 Antibody

Product Sizes
100 ug
£496.00
OAAF00239-100UG
About this Product
SKU:
OAAF00239
Additional Names:
aconitase 1; soluble;aconitate hydratase; cytoplasmic;ACONS;citrate hydro-lyase;cytoplasmic aconitase;cytoplasmic aconitate hydratase;cytosplasmic aconitase;epididymis luminal protein 60;epididymis secretory sperm binding protein;ferritin repressor protein;HEL60;IREB1;IREBP;IREBP1;iron regulatory protein 1;iron-responsive element-binding protein 1;IRP1;soluble aconitase.
Clonality:
Polyclonal
Extra Details:
Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake; sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
Gene Details:
aconitase 1
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human IREB1 around the phosphorylation site of Ser711.
Molecular Weight:
98 kDa
Protein Details:
Cytoplasmic aconitate hydratase
Purification:
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody