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Antibodies

C5AR1 Antibody

Product Sizes
100 ug
£496.00
OAAF00178-100UG
About this Product
SKU:
OAAF00178
Additional Names:
C5A;C5a anaphylatoxin chemotactic receptor;C5a anaphylatoxin chemotactic receptor 1;C5a anaphylatoxin receptor;C5a ligand;C5a-R;C5AR;C5R1;CD88;complement component 5a receptor 1.
Clonality:
Polyclonal
Extra Details:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994; PubMed:8182049; PubMed:7622471; PubMed:9553099; PubMed:10636859; PubMed:15153520; PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus; and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049; PubMed:7622471; PubMed:9553099). Receptor activation stimulates chemotaxis; granule enzyme release; intracellular calcium release and superoxide anion production (PubMed:10636859; PubMed:15153520).
Gene Details:
complement C5a receptor 1
Host:
Rabbit
Immunogen:
The antiserum was produced against synthesized peptide derived from human CD88/C5aR around the phosphorylation site of Ser338.
Molecular Weight:
39 kDa
Protein Details:
C5a anaphylatoxin chemotactic receptor 1
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Shipping Conditions:
Blue Ice
Storage Conditions:
-20Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody