TFRC Antibody
Product Sizes
100 ug
£496.00
OAAF00177-100UG
About this Product
- SKU:
- OAAF00177
- Additional Names:
- CD71;Golli-MBP;IMD46;myelin A1 protein;myelin basic protein;myelin membrane encephalitogenic protein;p90;proline-rich proteoglycan 2;T9;TFR;TFR1;TR;transferrin receptor protein 1;TRFR.
- Clonality:
- Polyclonal
- Extra Details:
- Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand; the heditary hemochromatosis protein HFE; competes for binding with transferrin for an overlapping C-terminal binding site. Positively regulates T and B cell proliferation through iron uptake (PubMed:26642240).
- Gene Details:
- myelin basic protein|transferrin receptor
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CD71/TfR around the phosphorylation site of Ser24.
- Molecular Weight:
- 84 kDa
- Protein Details:
- Transferrin receptor protein 1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
