BLM Antibody
Product Sizes
100 ug
£496.00
OAAF00142-100UG
About this Product
- SKU:
- OAAF00142
- Additional Names:
- Bloom syndrome protein;Bloom syndrome RecQ like helicase;Bloom syndrome; RecQ helicase-like;BS;DNA helicase; RecQ-like type 2;MGRISCE1;recQ protein-like 3;RECQ2;RECQL2;RECQL3.
- Clonality:
- Polyclonal
- Extra Details:
- ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction (PubMed:9388193; PubMed:24816114; PubMed:25901030). Participates in DNA replication and repair (PubMed:12019152; PubMed:21325134; PubMed:23509288). Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA (PubMed:21325134). Negatively regulates sister chromatid exchange (SCE) (PubMed:25901030). Stimulates DNA 4-way junction branch migration and DNA Holliday junction dissolution (PubMed:25901030). Binds single-stranded DNA (ssDNA); forked duplex DNA and DNA Holliday junction (PubMed:20639533; PubMed:24257077; PubMed:25901030).
- Gene Details:
- BLM RecQ like helicase
- Host:
- Rabbit
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Bloom Syndrome around the phosphorylation site of Thr99.
- Isotype:
- IgG
- Molecular Weight:
- 159 kDa
- Protein Details:
- Bloom syndrome protein
- Purification:
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
