4E-BP1 Antibody
Product Sizes
0.1 mg
£500.00
OAAD00441-0.1MG
About this Product
- SKU:
- OAAD00441
- Additional Names:
- PH; 4e-bp; 4e-bp1; PHAS-I; AA959816
- translate.label.attr.clone:
- 11G12C11
- Clonality:
- Monoclonal
- Extra Details:
- 4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1); also called ELF4EBP1/BP- 1/PHAS-I ; which is located on chromosome 8p12; with 118-amino acid protein (about 13kDa). Binding of eIF4EBP1 to eIF4E is reversible and is depen- dent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while(24kDa); the phosphorylated form will not. Akt; TOR; MAP kinase; S6 kinase; and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35; 45; 69 or serine 64. Although; not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
- Host:
- Mouse
- Isotype:
- IgG1
- Protein Details:
- Eukaryotic translation initiation factor 4E-binding protein 1
- Shipping Conditions:
- Blue Ice
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
