CD86 Antibody
Product Sizes
0.1ml
£522.00
OAAD00377-0.1ML
About this Product
- SKU:
- OAAD00377
- Additional Names:
- B70; B7-2; B7.2; LAB72; CD28LG2
- translate.label.attr.clone:
- 1B3
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells; and it is the ligand for two proteins at the cell surface of T cells; CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described; but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.
- Host:
- Mouse
- Immunogen:
- Purified recombinant fragment of human CD86 expressed in E. Coli.
- Isotype:
- IgG1
- Molecular Weight:
- 52kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C; for long term storage; store at -20C.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
