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Antibodies

AKT2 Antibody

Product Sizes
0.1ml
£522.00
OAAD00346-0.1ML
About this Product
SKU:
OAAD00346
Additional Names:
PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA
translate.label.attr.clone:
1B6
Clonality:
Monoclonal
Extra Details:
Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ); with 481-amino acid protein (about 53kDa); belongs to the AKT serine/threonine protein kinase family; which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation; differentiation; apoptosis; tumorigenesis; as well as glycogen synthesis and glucose uptake. Among the members of AKT family; Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus; plays an important role in chemoresistance. Further; Akt2 plays a specific role in muscle differentiation.
Host:
Mouse
Immunogen:
Purified recombinant fragment of human AKT2 expressed in E. Coli.
Isotype:
IgG2b
Molecular Weight:
60kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4C; for long term storage; store at -20C.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody