EP300 Antibody
Product Sizes
0.1ml
£522.00
OAAD00274-0.1ML
About this Product
- SKU:
- OAAD00274
- Additional Names:
- p300; KAT3B; MKHK2; RSTS2
- translate.label.attr.clone:
- 7D8A6
- Clonality:
- Monoclonal
- Extra Details:
- EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha); and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
- Host:
- Mouse
- Immunogen:
- Purified recombinant fragment of EP300 expressed in E. Coli.
- Isotype:
- IgG1
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C; for long term storage; store at -20C.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
