IFN-GAMMA Antibody
Product Sizes
0.1mg
£522.00
OAAD00252-0.1MG
About this Product
- SKU:
- OAAD00252
- Additional Names:
- IFG; IFI; IMD69
- translate.label.attr.clone:
- 1B1A4; E8H1
- Clonality:
- Monoclonal
- Extra Details:
- IFN-gamma (interferon; gamma) is an antiviral and antiparasitic agent produced by CD4+/CD8+ lymphocytes and natural killer cells that undergo activation by antigens; mitogens or alloantigens. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses; including the activation; growth and differentiation of T cell; B cells; macrophages; NK cells and other cell types such as endothelial cells and fibroblasts. The active form of IFN-G is a homodimer with each subunit containing six helices. The dimeric structure of human IFN-G is stabilized by non-covalent interactions through the interface of the helices. IFN-G translated precursor is 166 amino acids; including the 23 amino acid secretory sequence. It is upregulated by IL2; FGF basic; EGF and downregulated by vitamin D3 or DMN. Multiple forms exist due to variable glycosylation and under non-denaturing conditions due to dimers and tetramers.
- Host:
- Mouse
- Immunogen:
- Recombinant human IFN-gamma (BioSource company; Cat.No. PHC4033)
- Isotype:
- IgG1
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C; for long term storage; store at -20C.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
