RB Antibody
Product Sizes
0.1ml
£500.00
OAAD00229-0.1ML
About this Product
- SKU:
- OAAD00229
- Additional Names:
- RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1
- translate.label.attr.clone:
- 7E4B8
- Clonality:
- Monoclonal
- Extra Details:
- The Rb protein regulates differentiation; apoptosis; and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1; cyclin D-dependent kinase-mediated phosphorylation of Rb at Ser-795 marks the conversion of Rb from a transcriptionally repressive; hypophosphorylated state to an inactive; phosphorylated state; which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues. Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tumor suppressor gene(Rb).
- Host:
- Mouse
- Immunogen:
- Purified recombinant fragment of human RB expressed in E. Coli.
- Isotype:
- IgG1
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4C; for long term storage; store at -20C.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
