C-MYC Antibody
Product Sizes
100 ug
£431.00
OAAD00143-100UG
About this Product
- SKU:
- OAAD00143
- Additional Names:
- MRTL; MYCC; c-Myc; bHLHe39
- translate.label.attr.clone:
- IMD-3
- Clonality:
- Monoclonal
- Extra Details:
- C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization; and to a lesser extent the transformation of cells; in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division; and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to residues 408-439 of the human p62c-Myc protein.
- Isotype:
- IgG2a
- Protein Details:
- Myc proto-oncogene protein
- Purification:
- Purified by the goat anti-mouse IgG Affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- At -20C for one year. After reconstitution; at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
