BMPR2 Antibody - N-terminal region
Product Sizes
400ul
£597.00
OAAB20941-400UL
About this Product
- SKU:
- OAAB20941
- Additional Names:
- BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II
- translate.label.attr.clone:
- RB1806
- Clonality:
- Polyclonal
- Concentration:
- 2 mg/mL
- Extra Details:
- This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs; which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors; but they require their respective type I receptors for signaling; whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension; both familial and fenfluramine-associated; and with pulmonary venoocclusive disease.
- Gene Details:
- bone morphogenetic protein receptor type II
- Host:
- Rabbit
- Immunogen:
- This BMPR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27~56 amino acids from the N-terminal region of human BMPR2.
- Isotype:
- Rabbit Ig
- Molecular Weight:
- 115 kDa
- Purification:
- SAS precipitation; followed by dialysis against PBS
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
