ANAPC2 Antibody - C-terminal region
Product Sizes
400ul
£615.00
OAAB19015-400UL
About this Product
- SKU:
- OAAB19015
- Additional Names:
- APC2
- Clonality:
- Polyclonal
- Extra Details:
- Component of the anaphase promoting complex/cyclosome (APC/C); a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and; to a lower extent; the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.
- Host:
- Rabbit
- Immunogen:
- This ANAPC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 712-746 amino acids from the C-terminal region of human ANAPC2.
- Isotype:
- Rabbit Ig
- Molecular Weight:
- 94 kDa
- Purification:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
