MAPT Antibody - C-terminal region
Product Sizes
400ul
£597.00
OAAB18950-400UL
About this Product
- SKU:
- OAAB18950
- Additional Names:
- TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; tau-40; FTDP-17; PPP1R103
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Promotes microtubule assembly and stability; and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components; suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
- Host:
- Rabbit
- Immunogen:
- This MAPT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 694-728 amino acids from the C-terminal region of human MAPT.
- Isotype:
- Rabbit Ig
- Molecular Weight:
- 79 kDa
- Purification:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
