GPR56 Antibody
Product Sizes
400ul
£615.00
OAAB18677-400UL
About this Product
- SKU:
- OAAB18677
- Additional Names:
- BFPP; BPPR; GPR56; TM7LN4; TM7XN1
- translate.label.attr.clone:
- 1443CT377.65.29
- Clonality:
- Monoclonal
- Extra Details:
- Involved in cell adhesion and probably in cell-cell interactions. Regulates the migration of neural precursor cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development; specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Isoforms show differences in receptor signaling; specifically in serum response element (SRE) transcriptional activation upon overexpression. Overexpression inhibits melanoma tumor growth and metastasis and; during melanoma progression; regulates VEGFA production and angiogenesis through PRKCA; unprocessed GPR56 is inhibiting and GPR56 NT is activating angiogenesis.
- Host:
- Mouse
- Immunogen:
- This antibody is generated from a mouse immunized with a recombinant protein.
- Isotype:
- IgG1; k
- Molecular Weight:
- 78 kDa
- Purification:
- This antibody is purified through a protein G column; followed by dialysis against PBS.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
