HTR1A Antibody - middle region
Product Sizes
400ul
£615.00
OAAB18138-400UL
About this Product
- SKU:
- OAAB18138
- Additional Names:
- G-21; 5HT1a; PFMCD; 5-HT1A; 5-HT-1A; ADRBRL1; ADRB2RL1
- Clonality:
- Polyclonal
- Extra Details:
- G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors; such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain; and thereby affects neural activity; mood and behavior. Plays a role in the response to anxiogenic stimuli.
- Host:
- Rabbit
- Immunogen:
- This HTR1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 239-273 amino acids from the Central region of human HTR1A.
- Isotype:
- Rabbit Ig
- Molecular Weight:
- 46 kDa
- Purification:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
