DDR1 Antibody - N-terminal region
Product Sizes
400ul
£597.00
OAAB17175-400UL
About this Product
- SKU:
- OAAB17175
- Additional Names:
- CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; CD167; EDDR1; MCK10; NTRK4; PTK3A
- Clonality:
- Polyclonal
- Concentration:
- Varies by lot. See vial for concentration.
- Extra Details:
- Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth; differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells; particularly in the kidney; lung; gastrointestinal tract; and brain. In addition; this protein is significantly over-expressed in several human tumors from breast; ovarian; esophageal; and pediatric brain. The gene is located on chromosome 6p21.3 in proximity to several HLA class I genes.
- Host:
- Rabbit
- Immunogen:
- This DDR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the N-terminal region of human DDR1.
- Isotype:
- Ig
- Molecular Weight:
- 101 kDa
- Protein Details:
- Epithelial discoidin domain-containing receptor 1
- Purification:
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
