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Antibodies

EphB3 Antibody - N-terminal region

Product Sizes
400ul
£615.00
OAAB17141-400UL
About this Product
SKU:
OAAB17141
Additional Names:
EK2; ETK2; HEK2; TYRO6
Clonality:
Polyclonal
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Extra Details:
Ephrin receptors and their ligands; the ephrins; mediate numerous developmental processes; particularly in the nervous system. Based on their structures and sequence relationships; ephrins are divided into the ephrin-A (EFNA) class; which are anchored to the membrane by a glycosylphosphatidylinositol linkage; and the ephrin-B (EFNB) class; which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB3; a member of the Tyr family of protein kinases; is a receptor for members of the ephrin-B family; it binds to both ephrin-B1 and -B2. Expression of this Type I membrane protein is ubiquitous. The protein contains putative domains for 2 fibronectin type III and 1 sterile alpha motif (SAM).
Host:
Rabbit
Immunogen:
This EphB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-59 amino acids from the N-terminal region of human EphB3.
Isotype:
Ig
Molecular Weight:
110330 Da
Protein Details:
Ephrin type-B receptor 3
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Shipping Conditions:
Blue Ice
Storage Conditions:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody