Beclin 1 Antibody
Product Sizes
400ul
£615.00
OAAB13689-400UL
About this Product
- SKU:
- OAAB13689
- Additional Names:
- ATG6; VPS30; beclin1
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells; it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure; which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Beclin 1 plays a role in two fundamentally important cell biological pathways: autophagy and apoptosis. Beclin 1 is thought to function as a VPS and autophagy protein as part of a complex with Class III PI3 kinase; Vps34.
- Host:
- Rabbit
- Immunogen:
- This Beclin 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from human Beclin 1.
- Isotype:
- Ig
- Molecular Weight:
- 51896 Da
- Protein Details:
- Beclin-1
- Purification:
- This antibody is purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
