APG5 Antibody
Product Sizes
400ul
£615.00
OAAB13609-400UL
About this Product
- SKU:
- OAAB13609
- Additional Names:
- ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE
- Clonality:
- Polyclonal
- Concentration:
- Approximately 0.5mg/ml. Actual concentration varies with each lot.
- Extra Details:
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells; it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure; which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG5; required for autophagy; conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may also play an important role in the apoptotic process; possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process; occurring downstream of caspase activity.
- Host:
- Rabbit
- Immunogen:
- This ATG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the full length of human ATG5.
- Isotype:
- Ig
- Molecular Weight:
- 32 kDa
- Protein Details:
- Autophagy protein 5
- Purification:
- This antibody is purified through a protein A column; followed by dialysis against PBS.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
