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Antibodies

MGMT Antibody - N-terminal region

Product Sizes
400ul
£597.00
OAAB10146-400UL
About this Product
SKU:
OAAB10146
Additional Names:
MGMT; Methylated-DNA--protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase
Clonality:
Polyclonal
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Extra Details:
MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Host:
Rabbit
Immunogen:
This MGMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MGMT.
Isotype:
Rabbit Ig
Molecular Weight:
21646 Da
Protein Details:
Methylated-DNA--protein-cysteine methyltransferase
Purification:
This antibody is purified through a protein A column; followed by peptide affinity purification.
Shipping Conditions:
Blue Ice
Storage Conditions:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody