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Antibodies

CFB Antibody - middle region

Product Sizes
400ul
£597.00
OAAB05624-400UL
About this Product
SKU:
OAAB05624
Additional Names:
BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14
Clonality:
Polyclonal
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Extra Details:
CFB encodes complement factor B; a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway; it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes; while Ba inhibits their proliferation.
Host:
Rabbit
Immunogen:
This CFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 469-494 amino acids from the Central region of human CFB.
Isotype:
Rabbit Ig
Molecular Weight:
85533 Da
Protein Details:
Complement factor B
Purification:
This antibody is purified through a protein A column; followed by peptide affinity purification.
Shipping Conditions:
Blue Ice
Storage Conditions:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody