ANTXR1 Antibody
Product Sizes
400ul
£597.00
OAAB04785-400UL
About this Product
- SKU:
- OAAB04785
- Additional Names:
- ATR; GAPO; TEM8
- Clonality:
- Polyclonal
- Concentration:
- Approximately 0.5mg/ml. Actual concentration varies with each lot.
- Extra Details:
- ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin; the causative agent of the disease; anthrax. The binding of the protective antigen (PA) component; of the tripartite anthrax toxin; to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell; the other two components of anthrax toxin; edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
- Host:
- Rabbit
- Immunogen:
- This ANTXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-386 amino acids from human ANTXR1.
- Isotype:
- Rabbit Ig
- Molecular Weight:
- 63 kDa
- Protein Details:
- Anthrax toxin receptor 1
- Purification:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
