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Antibodies

EPHA3 Antibody - N-terminal region

Product Sizes
400ul
£597.00
OAAB04655-400UL
About this Product
SKU:
OAAB04655
Additional Names:
EK4; ETK; HEK; ETK1; HEK4; TYRO4
Clonality:
Polyclonal
Concentration:
2 mg/ml
Extra Details:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor; generally the g phosphate of ATP; onto an acceptor amino acid in a substrate protein. By this basic mechanism; protein kinases mediate most of the signal transduction in eukaryotic cells; regulating cellular metabolism; transcription; cell cycle progression; cytoskeletal rearrangement and cell movement; apoptosis; and differentiation. With more than 500 gene products; the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation; adhesion; motility and death. There are currently about 90 TK genes sequenced; 58 are of receptor protein TK (e.g. EGFR; EPH; FGFR; PDGFR; TRK; and VEGFR families); and 32 of cytosolic TK (e.g. ABL; FAK; JAK; and SRC families).
Host:
Rabbit
Immunogen:
This EphA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the N-terminal region of human EphA3.
Isotype:
Rabbit Ig
Molecular Weight:
110 kDa
Protein Details:
Ephrin type-A receptor 3
Purification:
This antibody is purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Shipping Conditions:
Blue Ice
Storage Conditions:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody