ALS2 Antibody - C-terminal region
Product Sizes
400ul
£597.00
OAAB03484-400UL
About this Product
- SKU:
- OAAB03484
- Additional Names:
- ALSJ; PLSJ; IAHSP; ALS2CR6
- Clonality:
- Polyclonal
- Concentration:
- Approximately 0.5mg/ml. Actual concentration varies with each lot.
- Extra Details:
- ALS2 contains an ATS1/RCC1-like domain; a RhoGEF domain; and a vacuolar protein sorting 9 (VPS9) domain; all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments; and functions as a modulator for endosomal dynamics. Mutations in its gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis.
- Host:
- Rabbit
- Immunogen:
- This ALS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1248-1277 amino acids from the C-terminal region of human ALS2.
- Isotype:
- Rabbit Ig
- Molecular Weight:
- 183666 Da
- Protein Details:
- Alsin
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
