S100B Antibody
Product Sizes
400ul
£597.00
OAAB02489-400UL
About this Product
- SKU:
- OAAB02489
- Additional Names:
- NEF; S100; S100-B; S100beta
- Clonality:
- Polyclonal
- Concentration:
- Approximately 0.5mg/ml. Actual concentration varies with each lot.
- Extra Details:
- S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells; and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however; this gene is located at 21q22.3. This protein may function in Neurite extension; proliferation of melanoma cells; stimulation of Ca2+ fluxes; inhibition of PKC-mediated phosphorylation; astrocytosis and axonal proliferation; and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological; neoplastic; and other types of diseases; including Alzheimer's disease; Down's syndrome; epilepsy; amyotrophic lateral sclerosis; melanoma; and type I diabetes.
- Host:
- Rabbit
- Immunogen:
- This S100B antibody is generated from rabbits immunized with S100B recombinant protein.
- Isotype:
- Rabbit Ig
- Molecular Weight:
- 11 kDa
- Protein Details:
- Protein S100-B
- Purification:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
