CTLA4 Antibody - N-terminal region
Product Sizes
200ul
£597.00
OAAB00477-200UL
About this Product
- SKU:
- OAAB00477
- Additional Names:
- CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
- Clonality:
- Polyclonal
- Concentration:
- 0.36 mg/ml
- Extra Details:
- CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain; a transmembrane domain; and a cytoplasmic tail. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond; while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus; Graves disease; Hashimoto thyroiditis; celiac disease; systemic lupus erythematosus; thyroid-associated orbitopathy; and other autoimmune diseases.
- Host:
- Rabbit
- Immunogen:
- This IDDM12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids of human IDDM12.
- Isotype:
- Rabbit Ig
- Molecular Weight:
- 25 kDa
- Protein Details:
- Cytotoxic T-lymphocyte protein 4
- Purification:
- This antibody is purified through a protein A column; followed by peptide affinity purification.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
