AKT1 antibody - N-terminal region
Product Sizes
25ul
£177.00
AVARP06008-P050-25UL
100 ul
£412.00
AVARP06008-P050-100UL
About this Product
- SKU:
- AVARP06008-P050
- Additional Names:
- AKT; PKB; RAC; PRKBA; PKB-ALPHA; RAC-ALPHA
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- AKT1 is a general protein kinase capable of phosphorylating several known proteins.The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific; and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1; which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene.
- Gene Details:
- V-akt murine thymoma viral oncogene homolog 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human AKT1
- Molecular Weight:
- 56kDa
- Protein Details:
- RAC-alpha serine/threonine-protein kinase
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
