CDK8 antibody - C-terminal region
Product Sizes
25ul
£177.00
AVARP03050-T100-25UL
100 ul
£373.00
AVARP03050-T100-100UL
About this Product
- SKU:
- AVARP03050-T100
- Additional Names:
- K35; IDDHBA
- Clonality:
- Polyclonal
- Concentration:
- 1.0 mg/ml
- Extra Details:
- The protein encoded by CDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28; and Schizosaccharomyces pombe cdc2; and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex; which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH); thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.
- Gene Details:
- Cyclin-dependent kinase 8
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human CDK8
- Molecular Weight:
- 53kDa
- Protein Details:
- Cyclin-dependent kinase 8
- Purification:
- Protein A purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
