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Antibodies

TNFRSF18 antibody - C-terminal region

Product Sizes
25ul
£177.00
AVARP02052-T100-25UL
100 ul
£373.00
AVARP02052-T100-100UL
About this Product
SKU:
AVARP02052-T100
Additional Names:
AITR; GITR; CD357; GITR-D; ENERGEN
Clonality:
Polyclonal
Concentration:
1.0 mg/ml
Extra Details:
The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation; and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation; and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Gene Details:
Tumor necrosis factor receptor superfamily; member 18
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human TNFRSF18
Molecular Weight:
23kDa
Protein Details:
Tumor necrosis factor receptor superfamily; member 18 EMBL CAI23248.1
Purification:
Protein A purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody