TNFSF14 antibody - middle region
Product Sizes
25ul
£177.00
AVARP02041-P050-25UL
100 ul
£412.00
AVARP02041-P050-100UL
About this Product
- SKU:
- AVARP02041-P050
- Additional Names:
- LTg; CD258; HVEML; LIGHT
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- TNFSF14 is the cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B TNFSF14 modulates its effects. TNFSF14 activates NFKB; stimulates the proliferation of T-cells; and inhibits growth of the adenocarcinoma HT-29. TNFSF14 acts as a receptor for Herpes simplex virus.The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14; which is a member of the tumor necrosis factor receptor superfamily; and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells; and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
- Gene Details:
- Tumor necrosis factor (ligand) superfamily; member 14
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human TNFSF14
- Molecular Weight:
- 22kDa
- Protein Details:
- Tumor necrosis factor ligand superfamily member 14
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
