TNFSF10
Product Sizes
25ul
£177.00
AVARP02040-P050-25UL
100 ul
£412.00
AVARP02040-P050-100UL
About this Product
- SKU:
- AVARP02040-P050
- Additional Names:
- TL2; APO2L; CD253; TRAIL; Apo-2L; TNLG6A
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- TNFSF10 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells; but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1; TNFRSF10B/TRAILR2; TNFRSF10C/TRAILR3; TNFRSF10D/TRAILR4; and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3; TNFRSF10D/TRAILR4; and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK; caspase 8; and caspase 3.
- Gene Details:
- Tumor necrosis factor (ligand) superfamily; member 10
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human TNFSF10
- Molecular Weight:
- 33kDa
- Protein Details:
- Tumor necrosis factor ligand superfamily member 10
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
