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Antibodies

Anti-PHOX2B

Product Sizes
25ul
£177.00
ARP97846-P050-25UL
100 ul
£412.00
ARP97846-P050-100UL
About this Product
SKU:
ARP97846-P050
Additional Names:
CCHS; PMX2B; NBLST2; NBPhox
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase; c-fos promoters and several enhancers; including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.
Gene Details:
paired like homeobox 2b
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human PHOX2B
Molecular Weight:
34 kDa
Protein Details:
paired mesoderm homeobox protein 2B
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody