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Antibodies

IL6ST Antibody Middle region

Product Sizes
25ul
£177.00
ARP97690-P050-25UL
100 ul
£412.00
ARP97690-P050-100UL
About this Product
SKU:
ARP97690-P050
Additional Names:
CD130; GP130; HIES4; CDW130; IL-6RB; sGP130
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The protein encoded by this gene is a signal transducer shared by many cytokines; including interleukin 6 (IL6); ciliary neurotrophic factor (CNTF); leukemia inhibitory factor (LIF); and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6; a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus; can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Gene Details:
interleukin 6 signal transducer
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human IL6ST
Molecular Weight:
94 kDa
Protein Details:
interleukin-6 receptor subunit beta
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody