ATF1 Antibody-C-terminal region
Product Sizes
25ul
£177.00
ARP97646-P050-25UL
100 ul
£412.00
ARP97646-P050-100UL
About this Product
- SKU:
- ARP97646-P050
- Additional Names:
- TREB36; EWS-ATF1; FUS/ATF-1
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes an activating transcription factor; which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes; which are related to growth; survival; and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases; cAMP-dependent protein kinase A; calmodulin-dependent protein kinase I/II; mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities; and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.
- Gene Details:
- activating transcription factor 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human ATF1
- Molecular Weight:
- 25 kDa
- Protein Details:
- cyclic AMP-dependent transcription factor ATF-1
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
