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Antibodies

Casp1 Antibody Middle region

Product Sizes
25ul
£177.00
ARP97640-P050-25UL
100 ul
£412.00
ARP97640-P050-100UL
About this Product
SKU:
ARP97640-P050
Additional Names:
IC; ICE; Il1; Casp; Il1bc
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Thiol protease that cleaves IL-1 beta between an Asp and an Ala; releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis (By similarity). Upon inflammasome activation; during DNA virus infection but not RNA virus challenge; controls antiviral immunity through the cleavage of CGAS; rendering it inactive.
Gene Details:
caspase 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of mouse CASP1
Molecular Weight:
44 kDa
Protein Details:
caspase-1
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody