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Antibodies

TP53 Antibody Middle region

Product Sizes
25ul
£177.00
ARP97250-P050-25UL
100 ul
£412.00
ARP97250-P050-100UL
About this Product
SKU:
ARP97250-P050
Additional Names:
P53; BCC7; LFS1; BMFS5; TRP53
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a tumor suppressor protein containing transcriptional activation; DNA binding; and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes; thereby inducing cell cycle arrest; apoptosis; senescence; DNA repair; or changes in metabolism. Mutations in this gene are associated with a variety of human cancers; including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants.
Gene Details:
tumor protein p53
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human TP53
Molecular Weight:
43 kDa
Protein Details:
cellular tumor antigen p53
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody