Anti-ALOXE3
Product Sizes
25ul
£177.00
ARP96877-P050-25UL
100 ul
£412.00
ARP96877-P050-100UL
About this Product
- SKU:
- ARP96877-P050
- Additional Names:
- ARCI3; E-LOX; eLOX3; eLOX-3
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene is a member of the lipoxygenase family; which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R;12R-epoxyeicosa-5Z;9E;14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha); which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis; implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- arachidonate lipoxygenase 3
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human ALOXE3
- Molecular Weight:
- 92 kDa
- Protein Details:
- hydroperoxide isomerase ALOXE3
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
