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Antibodies

Anti-CASR

Product Sizes
25ul
£177.00
ARP96813-P050-25UL
100 ul
£412.00
ARP96813-P050-100UL
About this Product
SKU:
ARP96813-P050
Additional Names:
CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; hCasR; GPRC2A; HYPOC1
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland; and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling; thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia; familial; isolated hypoparathyroidism; and neonatal severe primary hyperparathyroidism.
Gene Details:
calcium sensing receptor
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle terminal region of human CASR
Molecular Weight:
119 kDa
Protein Details:
extracellular calcium-sensing receptor
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody