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Antibodies

Anti-USH1C

Product Sizes
25ul
£177.00
ARP96739-P050-25UL
100 ul
£412.00
ARP96739-P050-100UL
About this Product
SKU:
ARP96739-P050
Additional Names:
PDZ73; AIE-75; DFNB18; PDZ-45; PDZ-73; PDZD7C; DFNB18A; NY-CO-37; NY-CO-38; ush1cpst; PDZ-73/NY-CO-38
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Anchoring/scaffolding protein that is a part of the functional network formed by USH1C; USH1G; CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles (By similarity). As part of the intermicrovillar adhesion complex/IMAC plays a role in brush border differentiation; controlling microvilli organization and length. Probably plays a central regulatory role in the assembly of the complex; recruiting CDHR2; CDHR5 and MYO7B to the microvilli tips.
Gene Details:
Usher syndrome 1C
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human USH1C
Molecular Weight:
46 kDa
Protein Details:
harmonin
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody