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Antibodies

Anti-VRK1

Product Sizes
25ul
£177.00
ARP96723-P050-25UL
100 ul
£412.00
ARP96723-P050-100UL
About this Product
SKU:
ARP96723-P050
Additional Names:
PCH1; PCH1A
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis; required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA; reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.
Gene Details:
vaccinia related kinase 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human VRK1
Molecular Weight:
45 kDa
Protein Details:
serine/threonine-protein kinase VRK1
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody