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Antibodies

Anti-Tmem59

Product Sizes
25ul
£177.00
ARP93888-P050-25UL
100 ul
£412.00
ARP93888-P050-100UL
About this Product
SKU:
ARP93888-P050
Additional Names:
ORF18; MTDCF1; AI256529; D4Ertd20; D4Ertd20e; 1110001M20Rik; 3110046P06Rik
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A; MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1; leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP; BACE1; SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.
Gene Details:
transmembrane protein 59
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle terminal region of mouse TMEM59
Molecular Weight:
36 kDa
Protein Details:
transmembrane protein 59
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody