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Antibodies

Maf Antibody Middle region

Product Sizes
25ul
£177.00
ARP88829-P050-25UL
100 ul
£412.00
ARP88829-P050-100UL
About this Product
SKU:
ARP88829-P050
Additional Names:
c-ma; c-maf; AW047063; 2810401A20Rik; A230108G15Rik
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic; macrophage; osteoclast; podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6; transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter. Involved either as an oncogene or as a tumor suppressor; depending on the cell context.
Gene Details:
avian musculoaponeurotic fibrosarcoma oncogene homolog
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of mouse MAF
Molecular Weight:
35 kDa
Protein Details:
transcription factor Maf
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody