Anti-MRVI1
Product Sizes
25ul
£177.00
ARP88721-P050-25UL
100 ul
£412.00
ARP88721-P050-100UL
About this Product
- SKU:
- ARP88721-P050
- Additional Names:
- IRAG; JAW1L; MRVI1
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein; which is found in the membrane of the endoplasmic reticulum; is similar to Jaw1; a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation; and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene; and alternative translation start sites; including a non-AUG (CUG) start site; are used.
- Gene Details:
- murine retrovirus integration site 1 homolog
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human MRVI1
- Molecular Weight:
- 97 kDa
- Protein Details:
- protein MRVI1
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
